The diagnosis relies on the accumulation of various criteria including clinical, about endoscopical, histological and biological findings. Table1: Initial symptoms about of UC. Extra intestinal symptoms can be an initial manifestation or can occur later in the course about of the disease. The leading initial symptom of UC is diarrhea with blood and mucus, sometimes with about pain (Table 1).
about Symptoms, signs, and laboratory findings. In addition, many of the cytokines (interleukins 1 and 6, tumor necrosis factor) will activate an acute phase response, about resulting in fever and a rise in serum acute phase proteins. These mediators not only serve to amplify the immune and inflammatory response, but they also have direct effects on epithelial function, on endothelial about function (which may increase permeability and lead to ischaemia), and on repair mechanisms, thus increasing collagen synthesis. This about immunological activity is associated with the release of a vast array of cytokines, kinins, leukotriens, platelet activating factor (PAF) and reactive oxygen metabolites.